12th Annual Meeting of the American Society for Cellular and Computational Toxicology (ASCCT)

Monday 23rd October 2023

• 09.15-11.15: NAMs as Problem-Solvers: Chairs: Dr Maria Fortin and Dr Shaun McCullough
  • OR3 - Practical Application of New Approach Methods in Developmental and Reproductive Toxicity Testing (PDF 3.11 MB). Predrag Kukic¹, Paul Carmichael¹, Matthew Dent¹, Jade Houghton¹, Amer Jamalpoor², Luke Flatt², Hequn Li¹, Alistair Middleton¹, Gopal Pawar¹, Claire Peart¹, Katarzyna Przybylak¹, Magdalena Sawicka¹, Sandrine Spriggs¹, Ramya Rajagopal¹, Katy Wilson¹, Kathryn Wolton¹, Iris Muller¹ (¹Unilever, SEAC; ²Toxys)
• 12.30-13.30: Poster Session I: Integrating NAMs for Better Decision-Making
  • P07 - Making Safety Decisions for a Sunscreen Active Ingredient Using Next Generation Risk Assessment: Benzophenone 4 Case Study (PDF 2.38 MB). Matthew Dent¹, Sophie Cable¹, Nicola Hewitt², Jade Houghton¹, Hequn Li¹, Joe Reynolds¹, Predrag Kukic¹, Sharon Scott¹, Sophie Malcomber¹, Reuben Mascarenhas³, Camilla Alexander-White4, Maria Baltazar¹ (¹Unilever, SEAC; ²Cosmetics Europe; ³The Estée Lauder Companies Inc.; ⁴MKTox Consultancy)
  • P11 - An Exposure-Led Approach to Worker Safety Assessment of Sodium 2-Hydroxyethane Sulphonate Using New Approach Methodologies (PDF 938.21 KB). Carl Westmoreland¹, Catherine Breffa², Caroline Chaine³, Susann Fayyaz², Fabian Grimm², Steve Gutsell¹, Predrag Kukic¹, Reiko Kiwamoto¹, Moung Sook Lee², Colin Smith⁴, Willemien Wieland⁴, Adam Wood¹, Tristan Zellmann⁵ (¹Unilever; ²Clariant Produkte Deutschland GmbH; ³Vantage Specialty Chemicals; ⁴Environmental Resources Management Limited; ⁵Vantage Leuna GmbH)
• 16.40-18.00: Integrating NAMs for Better Application: Chairs: Dr William Bisson and Dr Stephen Edwards
  • OR12 - The SARA-ICE Model for Predicting Skin Sensitizer Potency (PDF 1.48 MB). Gavin Maxwell¹, Georgia Reynolds¹, Joe Reynolds¹, Nicola Gilmour¹, Judy Strickland², Emily N Reinke², Dori Germolec³, Jim Truax², Dave G Allen², Nicole Kleinstreuer3 (¹Unilever, SEAC; ²Inotiv; ³NIH/NIEHS/DTT/PTB/NICEATM)

Tuesday 24th October 2023

• 11.00-12.00 Poster Session II: Ecological Assessment, Mixtures, and Device
  • P18 - Advancing Animal-Free Environmental Safety Assessments of Cosmetics. Amelie Ott¹, Glauco Battagliarin², Marlies Bergheim³, Arnaud Boivin⁴, Bruno Campos⁵, Iain Davies⁶, Juliet Hodges⁵, Sascha Pawlowski², Harald Streicher⁷ (¹International Collaboration on Cosmetics Safety (ICCS); ²BASF; ³Henkel; ⁴L'Oréal; ⁵Unilever, SEAC; ⁶PCPC; ⁷Beiersdorf)
• 15.45-17.45 Workshop Session: Case Study on Integrating NAMs into Decision-Making: Chairs: Predrag Kukic¹, Gavin Maxwell¹, Kristie Sullivan² (¹Unilever, SEAC; ²Institute for In Vitro Sciences)

Wednesday 25th October 2023

• 09.00-11.00 CE 3: Putting Theory into Practice: Using in Vitro and Computational New Approach Methodologies (NAMs) in Human-Relevant Risk Assessment. Nicole Kleinstreuer¹, John Wambaugh², Joshua Harrill², Predrag Kukic3 (¹NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), NIEHS, Raleigh-Durham-Chapel Hill Area; ²US Environmental Protection Agency; ³Unilever, SEAC)