Chemical mechanisms for skin sensitization by aromatic compounds with hydroxy and amino groups13 August 2009Aptula AO, Enoch SJ, Roberts DW (2009). Chemical mechanisms for skin sensitization by aromatic compounds with hydroxy and amino groups. Chemical Research in Toxicology, 22, 1541-47Download the publication (Opens in a pop-up window )
Risk assessment of genotoxic mutagens with thresholds: A brief introduction2 August 2009Kirsch-Volders M, Gonzalez L, Carmichael PL, Kirkland D (2009). Risk assessment of genotoxic mutagens with thresholds: A brief introduction,. Mutation Research, 678, 72-75Download the publication (Opens in a pop-up window )
Thresholds for genotoxins and their application in risk assessment2 August 2009Aptula AO, Enoch SJ, Roberts DW (2009). Chemical mechanisms for skin sensitization by aromatic compounds with hydroxy and amino groups. Chemical Research in Toxicology, 22, 1541-47Download the publication (Opens in a pop-up window )
A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: eye irritation1 July 2009McNamee P, Hibatallah J, Costabel-Farkas M, Carsten G, Daisuke A, Dufour E, Hewitt NJ, Jones P, Kirst A, Varlet Le B, Macfarlane M, Marrec-Fairley M, Rowland J, Schellauf F, Scheel J (2009). A tiered approach to the use of alternatives to animal testing for the safety assessment...Download the publication (Opens in a pop-up window )
Exposure based waiving: The application of the toxicological threshold of concern (TTC) to inhalation exposure for aerosol ingredients in consumer products1 June 2009Carthew P, Clapp C, Gutsell SJ (2009). Exposure based waiving: The application of the toxicological threshold of concern (TTC) to inhalation exposure for aerosol ingredients in consumer products. Food and Chemical Toxicology, 47, 1287-95Download the publication (Opens in a pop-up window )
Assuring consumer safety without animals1 April 2009Westmoreland C, Holmes AM (2009). Assuring consumer safety without animals. Applications for tissue engineering Organogenesis, 5, 67-72Download the publication (Opens in a pop-up window )
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells2 March 2009Dearman RJ, Cumberbatch M, Maxwell G, Basketter DA, Kimber I (2009). Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells. Immunology, 126, 475-84Download the publication (Opens in a pop-up window )
Reactivity Profiling: Covalent Modification of Single Nucleophile Peptides for Skin Sensitization Risk Assessment16 February 2009Aleksic M, Thain E, Roger D, Saib O, Davies M, Li J, Aptula AO, Zazzeroni R (2009). Reactivity Profiling: Covalent Modification of Single Nucleophile Peptides for Skin Sensitization Risk Assessment. Toxicological Sciences, 108, 401–11Download the publication (Opens in a pop-up window )
A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine1 February 2009Jenkinson C, Jenkins RE, Maggs JL, Kitteringham NR, Aleksic M, Park BK, Naisbitt DJ (2009). A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine. Chemical Research in Toxicology, 22, 1172-80Download the publication (Opens in a pop-up window )
The permeability of large molecular weight solutes following particle delivery to air-interfaced cells that model the respiratory mucosa1 February 2009Grainger CI, Greenwell LL, Martin GP, Forbes B (2009). The permeability of large molecular weight solutes following particle delivery to air-interfaced cells that model the respiratory mucosa. European Journal of Pharmaceutics and Biopharmaceutics. 71, 318-24Download the publication (Opens in a pop-up window )
Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links15 January 2009Wu JH, Wilson JB, Wolfreys AM, Scott A, Jones NJ (2009). Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links. Mutagenesis, 24, 173-81Download the publication (Opens in a pop-up window )
Read-Across to Rank Skin Sensitization Potential: Subcategories for the Michael Acceptor Domain6 January 2009Schultz TW, Rogers K, Aptula AO (2009). Read-Across to Rank Skin Sensitization Potential: Subcategories for the Michael Acceptor Domain. Contact Dermatitis, 60, 21-31Download the publication (Opens in a pop-up window )
