Society of Environmental Toxicology and Chemistry Europe 34th Annual Meeting

The 34th SETAC Europe Annual Meeting to be held in Sevilla, Spain on the 5-9th May 2024 will gather approximately 2500 scientists and practitioners from Academia, Industry, Government and Civil Societies exploring the overarching theme "Science-Based Solutions in Times of Crisis: Integrating Science and Policy for Environmental Challenges.". Throughout the week SEAC Environmental Safety and Sustainability scientists and our network of external collaborators will contribute a substantial number of sessions, oral presentations and posters leading to discussions on latest scientific developments living up to SETAC slogan “Environmental Quality Through Science®”.

Unilever and Partners Oral Presentations

3.01.B.T-03 - Using An In Silico NAMs Approach To Predict Bioaccumulation In Fish: A Case Study For Anionic Surfactants Within A Regulatory Context

Jayne Roberts1, Andrea Gredelj1,2, Steve Gutsell1, Geoffrey Hodges1, James Dawick3, Lauren McAnally3 and Marc Geurts4, (1)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (2)Norwegian Geotechnical Institute (NGI), Oslo, Norway, (3)Innospec Limited, United Kingdom, (4)Nouryon Chemicals B.V., Arnhem, Netherlands

1.11.T-03 - Integration of Endocrine Modalities into an Existing Mechanism of Action-based In Silico Scheme for use in Environmental Risk Assessment

James W. Firman1, Franklin Bauer2, Geoffrey Hodges3, Gaspard Levet2, Bruno Campos3, Jayne Roberts3, Steve Gutsell3, Homa Basiri1, Paul Thomas2 and Mark Cronin1, (1)Liverpool John Moores University, United Kingdom, (2)KREATiS, France, (3)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom

1.11.T-04 - Predicting Aquatic Toxicity of Surfactants Using Simulated Coarse-Grained Membrane-Water Coefficient Derived QSARs

Andrea Gredelj1,2, Jayne Roberts1, Elin Barrett1, Eoin Kearney3, Nicola Haywood1, Mark Miller3 and Geoffrey Hodges1, (1)Unilever - Safety and Environmental Assurance Centre (SEAC), Sharnbrook, United Kingdom, (2)Norwegian Geotechnical Institute (NGI), Oslo, Norway, (3)Department of Chemistry, Durham University, Durham, United Kingdom

Unilever and Partners Poster Presentations

7.04.P-We570 - Sustainable product innovations for fast-moving consumer goods – Learning from companies’ experiences for a more effective and accessible ‘Safe and Sustainable by Design’ framework

Florence Bohnes, Ian Malcomber, Sarah Sim, David Mason, Gordon Riley, Clare Rodseth, Evita Vandenbossche-Goddard, Unilever R&D Colworth, Sharnbrook, United Kingdom

5.05.P-Mo495 - Improving substance coverage for more accurate ecotoxicity normalisation factors – A Consortium-based approach

Florence Bohnes1,2, Mathilde Kolenda2,3, Jad Zoghaib2,4, (1)Unilever R&D Colworth, Sharnbrook, United Kingdom, (2)EcoBeautyScore Consortium, (3)Quantis, Paris, France, (4)L'Oréal Recherche & Innovation, Paris, France

5.04.P-Tu497 - Improving the robustness of freshwater ecotoxicity impact assessment of cosmetic products in life cycle assessment: summary and illustration of the work conducted by the EcoBeautyScore Consortium

Alessio Aufoujal2, Florence Bohnes1, Laurent Gilbert3, Mathilde Kolenda2, Monica Lam4, Sacha Laruelle5, Jacques L'Haridon, PhD6, Olena Onyshchenko7, Jennifer K. Saxe8, Pascal Seel9, Harald Streicher10 and Jad Zoghaib11, (1)Unilever R&D Colworth, Sharnbrook, United Kingdom, (2)Quantis, Paris, France, (3)L’Oréal Recherche & Innovation, Aulnay-sous-Bois, France, (4)Procter & Gamble, ., United States, (5)LVMH Recherche Parfums & Cosmétiques, ., France, (6)L'Oréal Recherche & Innovation, Aulnay-sous-Bois, France, (7)Henkel AG & Co. KGaA., Düsseldorf, Germany, (8)KENVUE, Skillman, NJ, (9)Environmental Strategy & Human Rights, Beiersdorf, Germany, (10)Beiersdorf, Germany, (11)L'Oréal Recherche & Innovation, Paris, France

1.11.P-Th068 - Development of an Ontology-Driven In Silico Profiler for the Evaluation of Potential Endocrine Disruptors.

Mark Cronin1, Homa Basiri1, Franklin Bauer2, Bruno Campos3, James W. Firman1, Steve Gutsell3, Geoffrey Hodges3, Gaspard Levet2, Jayne Roberts3 and Paul Thomas2, (1)Liverpool John Moores University, United Kingdom, (2)KREATiS, France, (3)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom

3.01.P-Th136 - Assessment of Methods for Determining The Membrane-Water Partition Ratio for Surfactants

Steven Droge1, Nina Jansen1, Elin Barrett2, Adriana C. Bejarano3, Jens Bietz4, Kristin Connors5, James Dawick6, Marc Geurts7, Geoffrey Hodges2, Eoin Kearney8, Mark Miller8, Diederik Schowanek9 and Sabrina Wilhelm10, (1)Environmental Risk Assessment, Wageningen University & Research (WUR), Wageningen, Netherlands, (2)Safety and Environmental Assurance Centre, Unilever Research, Bedford, United Kingdom, (3)Shell Global Solutions, (4)Clariant Produkte (Deutschland) GmbH, Frankfurt am Main, Germany, (5)Procter & Gamble, Mason, (6)Innospec Limited, United Kingdom, (7)Nouryon Chemicals B.V., Arnhem, Netherlands, (8)Department of Chemistry, Durham University, Durham, United Kingdom, (9)Brussels Innovation Centre, Procter & Gamble, Brussels, Belgium, (10)BASF Personal Care and Nutrition GmbH, Germany

3.12.P-Tu247 - Coarse-Grained Simulations of Passive Partitioning of Ionic Surfactants into Cell Membranes

Eoin Kearney1, Mark Miller1, Elin Barrett2, Adriana C. Bejarano3, Jens Bietz4, Kristin Connors5, James Dawick6, Steven Droge7, Marc Geurts8, Geoffrey Hodges2, Diederik Schowanek9 and Sabrina Wilhelm10, (1)Department of Chemistry, Durham University, Durham, United Kingdom, (2)Unilever R&D Colworth, United Kingdom, (3)Shell Global Solutions, (4)Clariant Produkte (Deutschland) GmbH, Frankfurt am Main, Germany, (5)Procter & Gamble, (6)Innospec Limited, United Kingdom, (7)Environmental Risk Assessment, Wageningen University & Research (WUR), Wageningen, Netherlands, (8)Nouryon Chemicals B.V., Arnhem, Netherlands, (9)Brussels Innovation Centre, Procter & Gamble, Brussels, Belgium, (10)BASF Personal Care and Nutrition GmbH, Düsseldorf, Germany

4.02.P-Th443 - Assessing risks to biodiversity from exposure to chemicals: findings of an ECETOC Task Force on the regulatory context

Christoph Mayer1, David A Bohan2, Sian Ellis3, Anja Gladbach4, Volker Grimm5, Jutta Hellstern6, Geoffrey Hodges7, Sarah A. Hughes8, Philippe Lemaire9, Lorraine Maltby10, Anna-Maija Nyman11, Michael Riffel12, Hans Sanderson13, Aaron Stoler14, Marco Thines15, Johannes Tolls Dir16, Nico van den Brink17 and Nika Galic18, (1)BASF SE, Germany, (2)INRAe, (3)Corteva Agriscience, Abingdon, United Kingdom, (4)Bayer AG - Crop Science Division, ., Germany, (5)Helmholtz Centre for Environmental Research – UFZ, Germany, (6)F. Hoffmann-La Roche, (7)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (8)Shell Global Solutions, (9)Total Special Fluids Division, France, (10)School of Biosciences, University of Sheffield, Sheffield, United Kingdom, (11)European Chemicals Agency (ECHA), Helsinki, Finland, (12)RIFCON GmbH, Hirschberg, Germany, (13)Aarhus University, Denmark, (14)Exxon Mobil, Cypress, United States, (15)Goethe University, (16)Corporate Scientific Services, Henkel AG & Co. KGaA, Düsseldorf, Germany, (17)Division of Toxicology, Wageningen University & Research, Wageningen, Netherlands, (18)Syngenta AG, Switzerland

1.02.P-Mo003 - Ecdysone Receptor Agonism Adverse Outcome Pathway Validation for Insect-Specific In Vitro Assay Development

Rebeka Darmati1, Paul Carmichael2, Bruno Campos2 and Nico van den Brink1, (1)Division of Toxicology, Wageningen University & Research, Wageningen, Netherlands, (2)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom

1.08.P-Mo054 - Using Comparative Genomics to Develop ‘Digital Twins’ to Support Ecotoxicological Predictions

Rama Krishnan1, David Spurgeon2, Stephen James Short3, Bruno Campos4, Claudia Rivetti4, Claire Peart4 and Peter Kille1, (1)Cardiff University, United Kingdom, (2)UK Centre for Ecology & Hydrology (UKCEH), Wallingford, United Kingdom, (3)Pollution, UK Centre for Ecology & Hydrology (UKCEH), United Kingdom, (4)Unilever - Safety and Environmental Assurance Centre (SEAC), Unilever, United Kingdom

1.11.P-Th067 - Addressing the challenges of Acute Toxicity Hazard Classification using a non-animal Defined Approach

Donna S. Macmillan1, Pravin Ambure2, Yannick Bayona3, Vera Bonderovic4, James Dawick5, Nicolas Fabre3, Stephan Fischer6, Geoffrey Hodges7, Ágata Llobet Mut2, Sophie Loisel-Joubert3, Jayne Roberts7, Eva Serrano Candelas2, Blanca Serrano8, Claudia Rivetti7, Kristin Schirmer9 and Ricky Stackhouse10, (1)HSI, (2)ProtoQSAR, Spain, (3)L'Oréal Research & Innovation, France, (4)BioRevivo, (5)Innospec Limited, United Kingdom, (6)aQuaTox-Solutions GmbH, Switzerland, (7)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (8)ECETOC, Brussels, Belgium, (9)Environmental Toxicology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland, (10)Sasol, Houston, Texas

1.11.P-Th069 - MechoA+: use, versatility and structural diversity

Gaspard Levet1, Franklin Bauer1, James W. Firman2, Bruno Campos3, Steve Gutsell3, Jayne Roberts3, Mark A. Bonnell4, Paul Thomas1, Mark Cronin2 and Geoffrey Hodges3, (1)KREATiS SAS, L'Isle d'Abeau, France, (2)Liverpool John Moores University, United Kingdom, (3)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (4)Department of Environment and Climate Change Canada

3.17.P-Tu295 - Building Knowledge from Available Degradation Simulation Studies to Improve their Usability

Louise Camenzuli1, Michael Earl2, Katie Endersby3,4, Kathrin Fenner5, Richard Gibson6, Patricia Anna Golombek7, Jasmin Hafner8, Damian Helbling9, Christopher Hughes10, Aurelia Lapczynski11, Sven Peter12, David MV Saunders13, Chiara Maria Vitale14, Neil Wang15, Miriam Leon Paumen16, lemaire philippe17, Johannes Tolls Dir18 and Marie Collard19, (1)ExxonMobil, Belgium, (2)Syngenta Ltd.,, Jealott’s Hill, United Kingdom, (3)School of Life Sciences, University of Warwick, Coventry, United Kingdom, (4)Safety and Environmental Assurance Centre (SEAC), Unilever, Colworth Science Park, United Kingdom, (5)Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland, (6)UK Environment Agency, United Kingdom, (7)RG/TC, BASF SE, Germany, (8)Environmental Chemistry, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland, (9)Cornell University, (10)Ricardo, Harwell, United Kingdom, (11)Research Institute for Fragrance Materials, Woodcliff Lake, NJ, (12)GBP/RA, BASF SE, Germany, (13)Shell Global Solutions, ., Netherlands, (14)Procter & Gamble, Mason, United States, (15)Solvay, Lyon, France, (16)ExxonMobil Biomedical Sciences, Inc., Machelen, Belgium, (17)Total, (18)Corporate Scientific Services, Henkel AG & Co. KGaA, Düsseldorf, Germany, (19)DSM-Firmenich, Belgium

3.17.P-Tu296 - How do River Channel Geometry and Sediment Calibre Affect the Degradation of Wastewater Pollutants? Insights from a Laboratory Experiment

Robert Newbould1, Mark Powell1, Alexandre Teixeira2, Juliet Hodges2 and Mick Whelan1, (1)School of Geography, Geology and the Environment, University of Leicester, United Kingdom, (2)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom

3.02.P-We119 - Estimating Marine Chemical Emissions from Discharges of Sewage Treatment Plants into Freshwater Rivers

Logan Insinga1, Christopher M Holmes1 and Juliet Hodges2, (1)Applied Analysis Solutions, LLC, (2)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom

6.02.P-We501 - Addressing the Impact of the Mixture Allocation Factor (MAF) on Environmental Risk Assessment: Refining Regulatory Exposure Predictions Using Spatial Data and Modelling Approaches

Christopher M Holmes1, Logan Insinga1, Juliet Hodges2, Jens Bietz3, Liesa-Kristin Beuter Beuter4, Geoffrey Hodges2, Diederik Schowanek5, James Dawick6, Erin Maloney7, Marc Geurts8, Sabrina Wilhelm9, Susan A Csiszar10 and Henrique Anselmo11, (1)Applied Analysis Solutions, LLC, (2)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom, (3)Clariant Produkte (Deutschland) GmbH, Frankfurt am Main, Germany, (4)Nouryon AB, Niefern-Öschelbronn, Sweden, (5) Brussels Innovation Centre, Procter & Gamble, Brussels, Belgium, (6)Innospec Limited, United Kingdom, (7)Shell Global Solutions International BV, Den Haag, Netherlands, (8)Nouryon Chemicals B.V., Arnhem, Netherlands, (9)BASF Personal Care and Nutrition GmbH, Düsseldorf, Germany, (10)Procter & Gamble, Belgium, (11)Global Safety Assurance, Reckitt, Netherlands

3.17.P-Tu291 - Biodegradable or not? Developing a standardized international approach to assessing the biodegradability of cosmetic formulations

Silke Fiebig1, Juliet Hodges2, Amelie Ott3, Ryan Heisler3, Karina J Reynolds4, Andrea Carrao5, Guillaume Cottin6, Jennifer Dorts7, Judith Kaumanns8, Monica Lam9, Fanny Minetto10, Beta Montemayor11, Jennifer K. Saxe12, Harald Streicher13, Cyril Sweetlove14 and Nadin Wedler15, (1)Vitis Regulatory, Pean Hill, United Kingdom, (2)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom, (3)International Collaboration on Cosmetics Safety (ICCS), New York, (4)WSP E&I, United Kingdom, (5)Kao USA, (6)L'OREAL, France, (7)IFRA, (8)Product Safety & Regulatory Affairs, Wella Company, Darmstadt, Germany, (9)Procter & Gamble, ., United States, (10)Chanel, (11)Science, Regulation and Market Access, Cosmetics Alliance Canada, Mississauga, Canada, (12)Kenvue, (13)Beiersdorf, Hamburg, Germany, (14)L'Oréal, ., France, (15)Kao Germany GmbH, ., Germany

2.04.P-Tu077 - Multiple contaminants in complex communities: evaluating non-additive effects of multiple simultaneous stressors on biomass flux and ecosystem functioning

Hana B Mayall1, Lorraine Maltby1, Dylan Z Childs1, Claudia Rivetti2, Andrea Gredelj3 and Andrew Beckerman1, (1)School of Biosciences, University of Sheffield, Sheffield, United Kingdom, (2)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (3)Norwegian Geotechnical Institute (NGI), Oslo, Norway

4.04.P-We327 Predicting Extinctions in Food Webs

Thomas Malpas1, Lorraine Maltby2, Claudia Rivetti3 and Andrea Gredelj3, (1)University of Sheffield, Sheffield, United Kingdom, (2)School of Biosciences, University of Sheffield, Sheffield, United Kingdom, (3)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom

1.02.P-Mo002 - Screening Chemicals Using High-Throughput Phenotypic Profiling (HTPP) in Two Zebrafish Cell Lines

Felix Harris1, Clinton Willis2, Bruno Campos3, Geoffrey Hodges3, Sophie Cable3, Alistair Middleton3, Amanda Jurgelewicz4, Richard Judson2 and Joshua Austell Harrill2, (1)ORISE Participant at U.S. Environmental Protection Agency, (2)U.S. Environmental Protection Agency, (3)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (4)ORISE Participant at the U.S. Environmental Protection Agency

1.02.P-Mo005 - Breaking the silos: Towards a holistic approach of animal-free human and environmental health safety assessments of cosmetics

Amelie Ott1, Ryan Heisler1, David Allen2, Arnaud Boivin3, Maria Baltazar4, Bruno Campos5, Christopher Choi6, Carol Courage7, Iain Davies8, Nazanin Golbamaki9, Juliet Hodges10, Abdulkarim Najjar11, Véronique Poulsen12, Gladys Ouedraogo9, Andreas Schepky11 and Harald Streicher11, (1)International Collaboration on Cosmetics Safety (ICCS), New York, (2)Integrated Laboratory Systems, Inc., (3)L'Oréal, France, (4)Unilever, (5)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (6)Takasago, (7)Croda, (8)PCPC (Personal Care Products Council), (9)L'Oréal, (10)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom, (11)Beiersdorf, Germany, (12)l'OREAL, France

3.17.P-Tu287 - New Approaches to Persistence Testing With Increased Cell Number Using Tangential Flow Filtration.

Katie Endersby, Dave Gore and Chris Finnegan, Safety and Environmental Assurance Centre (SEAC), Unilever, Colworth Science Park, United Kingdom

4.02.P-Th444 - Assessing Risks to Biodiversity from Exposure to Chemicals: Findings of an ECETOC Task Force on Current and Future Research Directions

Anja Gladbach1, David A Bohan2, Sian Ellis3, Volker Grimm4, Jutta Hellstern5, Geoffrey Hodges6, Sarah A. Hughes7, Philippe Lemaire8, Lorraine Maltby9, Christoph Mayer10, Anna-Maija Nyman11, Michael Riffel12, Hans Sanderson13, Aaron Stoler14, Marco Thines15, Johannes Tolls Dir16, Nico van den Brink17 and Nika Galic18, (1)Bayer AG - Crop Science Division, Germany, (2)INRAe, (3)Corteva Agriscience, Abingdon, United Kingdom, (4)Helmholtz Centre for Environmental Research – UFZ, Germany, (5)F. Hoffmann-La Roche, (6)Unilever - Safety and Environmental Assurance Centre (SEAC), United Kingdom, (7)Shell Global Solutions, (8)Total Special Fluids Division, France, (9)School of Biosciences, University of Sheffield, Sheffield, United Kingdom, (10)BASF SE, Germany, (11)European Chemicals Agency (ECHA), Helsinki, Finland, (12)RIFCON GmbH, Hirschberg, Germany, (13)Aarhus University, Denmark, (14)Exxon Mobil, Cypress, United States, (15)Goethe University, (16)Corporate Scientific Services, Henkel AG & Co. KGaA, Düsseldorf, Germany, (17)Division of Toxicology, Wageningen University & Research, Wageningen, Netherlands, (18)Syngenta AG, Switzerland

3.07.P-Th301 - Biodegradability of Water-Soluble and Water-Dispersible Polymers in Respirometric Laboratory Methods

Glauco Battagliarin1, Kathleen McDonough2, Marlies Bergheim Sr M3, Jared Bozich4, Katie Endersby5, Dave Gore5, Bjoern Hidding6, Christian Kastner Sr M3, Jan Robinson7, Georg Kreutzer8, Hans Leijs9, Jennifer Menzies10, Meera Raghuram11 and Nathalie Vallotton12, (1)Research Biopolymers, BASF SE, Ludwigshafen am Rhein, Germany, (2)P&G, Mason, OH, (3)Corporate Scientific Services, Henkel AG & Co. KGaA, Düsseldorf, Germany, (4)International Flavors and Fragrances, (5)Safety and Environmental Assurance Centre

8.08.P-Tu548 - MERCI: A tiered exposure modeling framework to support the environmental risk assessment of cosmetic ingredients directly discharged into natural waters.

Ryan Heisler1, W. Martin Williams2, Maura Roberts2, Todd Gouin3, Scott Dyer2, Amelie Ott1, Sascha Pawlowski4, Juliet Hodges5, Arnaud Boivin6, Eva Klingelmann7 and Ahmed Tlili8, (1)International Collaboration on Cosmetics Safety (ICCS), (2)Waterborne Environmental, Inc., (3)TG Environmental Research, United Kingdom, (4)GBP/RA, BASF SE, Germany, (5)Safety & Environmental Assurance Centre, Unilever, Sharnbrook, United Kingdom, (6)L'Oréal, France, (7)Symrise AG, Germany, (8)Personal Care, DSM-Firmenich, Switzerland